Thursday, January 29, 2015

Human - ─░nsan [┼×iddetle Tavsiye Edilir] T├╝rk├že Altyaz─▒l─▒ Belgesel

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I remember my my you know my stepfather
you know would beat me and he you know
he would beat me with an extension cause
and and and hangers and you know pieces
of words and all kinds of stuff and you
know after every beating he would tell
me you know it hurt me more than hurts
you and you know I only did it because I
love you it was kind of you know it
communicated the wrong message to me
about what love was I so for many years
you know I thought that love was
supposed to hurt and I hurt everyone
that I love and I measured love by how
much pain someone would take from me and
it wasn't until I came to prison in an
environment that is devoid of love but I
began to have some sort of understanding
about what it actually was and was not
and I met someone and she gave me my
first real insight into what love was
because she saw past my conditions and
the fact that I was in prison with a
life sentence for murder not and not
only for murder but for doing the worst
kind of murder than a man can do
murdering a woman and a child and it was
Agnes the mother and grandmother of
Patricia and Chris the woman and child
that I murdered who gave me my best
lesson about love because by all rights
she saved me
but she didn't and over the course of
time and through the journey that we
took that's been pretty amazing
she gave me love and
she taught me what it was
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being in a wheelchair and traveling the
world new wheelchair I've seen life from
a different angle and that taught me on
a spiritual level to just accept and to
be happy what say whatever's coming next
I'm so mentally strong and the only
reason that has come is because of
losing my legs physically you know my
eyesight sharper my ears are I can hear
much better so that's not a physical
sense but I feel I'm lucky as in I don't
analyze or question life too much I can
I can cruise through life and and always
be in the right place at the right time
I always have amazing things happen to
me I'm really lucky in that situation
but that comes from believing in in luck
or believing in the power of attraction
or believing in in attracting the
goodness into one's life and I think
that can be seen as luck so if God
Himself jumped down in front of me right
now and said to me
Bruno I'll give you back your legs but
I'll take away all that you've learned
over the last 13 years
I'll tell God keep your legs
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one of the most impactful things that
will occur after being in combat is the
feeling of killing another human being
once you've experienced it you'll see
that it's not like anything else that
you've experienced before and
unfortunately that feeling
your body will want to experience again
it's it's really difficult to try to
explain to somebody explain to somebody
what that feelings like right now I
still feel like experiencing that again
and it's probably why I keep a lot of
weapon in my house I your nor desire for
someone to try to to hurt me or to break
in or to give me an excuse to use that
violence against somebody else again
in the 16th of January 2007 an Israeli
border police shot and killed my ten
years old daughter a beard in front of
head school in honor of a relief she was
with her sister and her girlfriends 9:30
in the morning in her head in the back
from a distance of 15 to 20 meters by an
apartment a beer wasn't a fighter she
was just a child she don't know anything
about the conflict and she is not part
of this conflict unfortunately she lost
her life because she's a Palestinian I'm
an Israeli Velocity's daughter to a
suicide bombing on the 4th of September
1997 and I'm a product of of an
education system these are two societies
at war and they socialize the younger
generation to make them being able to
sacrifice themselves when time comes and
this is true the Palestinian society and
this is also true to Israeli society
because we are human beings sometimes
you think if I kill the killer or anyone
from the other side from the Israelis or
maybe 10 this will give me back my
no I had caused another pain and another
victim to the others I decide to broke
the circle of violence and blood and
revenge by stop killing and revenge and
support revenge by myself
my definition of sides have changed
dramatically today on my side are all
those who want peace and are willing to
pay the price of
said the other side are those who do not
want peace and are not willing to pay
the price of peace many people told me
that it's not your right to forgive in
her name and the answer it's also not my
right to revenge and hefney I hope she
she's satisfied I hope she rest in peace
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after being married for 50 years 49 51
years but my wife took seriously ill
just before we celebrated our 50th
wedding anniversary
and she suffered terribly for about two
years as an invalid for the last two
years of her life I was her nurse I was
a doctor was her friend I was alive I
was her husband everybody wanted me to
get a nurse full-time nurse daya not
nurse and she begged me not to she only
wanted me to look after her and I loved
doing it for her and I did it on myself
I carried it to the car I carry the
oxygen tank I carried her wheelchair
pected in the car took it out I pushed
it around I put it back I took her home
a bother I put it abate and I loved it
that I was able to do it for her without
anyone else and she appreciated it let's
love the magic moment that I have with
my grandfather was right after my
grandmother died and I went to go see
him and I knew that he was hurting but I
wasn't sure what kind of state he would
be in and she was his partner 65 years
as well as his driver and I went to see
him and said grandpa how are you doing
he said did you know that for four
dollars I can get a shuttle anywhere in
the city nothing huh that's great
grandpa you said well I went to save on
I went to the grocery store and went to
the woman behind the counter and said I
have this list of things could you help
me find them my wife has recently
changed her residence to heaven and I
said grandpa man you hope he's helped me
see the glass is half-full and he leaned
back and he looked me in the eyes and he
said it's a beautiful glass
this the edema I love
I lost even that hard moves in love was
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tre cosas de en er um I think when I was
young I didn't think I was going to stay
in the community of religious that I was
had joined and I suppose I didn't
understand what I was actually doing and
that I was maybe making a decision which
meant that I wouldn't have children and
I wouldn't have a family as other people
had I didn't think I don't really think
I understood that but later in life I
had a sister who died of cancer and when
I saw her family I realized - when I
died there wouldn't be anybody to mourn
me in the same way
it is a time goes on then you recognize
that you are a parent to other people
who you work with or who are friends or
who are related to you in some way so
even though you haven't your own family
you have family so I think that's
important to me it's a delicate OS
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when I went and stayed with my with my
with my wife at her house in San
Francisco she's not my wife of the one
of mine with woman with she this was
about a week after we started dating and
I woke up in the morning and I said so
you know I ask this of you and this of
you and this of you and you know you're
but like the woman almost can't have an
a list of knows like it's gonna be
pretty much all yeses or we don't have a
I mean that's just where I'm at and it
took her about a month after I pointed
that out to her to realize that these
knows could not exist and so that's how
very little shitty my woman is she's
she's freaking very unique
very amazing she gives me like she was
raised to like adore her man like
old-school Mexican like know when to
speak up and that doesn't mean you can't
tell me something doesn't mean you can't
share that doesn't mean I don't want
guidance but in my household the man is
the man of the house okay I live in the
lubricant so much you feel like using it
and I'm even before eternity my diamond
give me
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and she reach out to me on phone whoa
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surely aunty the tender in her magazine
I my own guru doctor I said missing our
lodging about income and the either way
out of being abused for me it was tough
because I used to have the worst abuse I
would have a gun put to my head and it
told to go on my knees and beg for my in
my life and I would do it just my kids
used to be watching or I'll get put out
out of the house I get kicked out of the
house and have to sleep outside on the
steps and if I move from there we'll get
a hiding the next day it was tough
because I thought it was me I was the
one that was doing something wrong in
our marriage you know when I started
talking about my kids those are the most
important thing of my life and I thought
if I don't move on out of here I'm
either gonna be dead or my kids are
gonna be dead so I need to move on I
need to do something and I went home
that day and I said to him from leaving
um nothing's more got a bit of a shock
because he didn't realize that I was
leaving and he said no you never leave
me you've never will you will never
leave me you love me too much and I said
well you know what that's what love is
leaving and I gave him two choices and I
only gave him two choices I said to him
you hit the girl for counseling
I leave and you know what today he's a
bit of man he's never lifted a hand up
for me
ever since the day it's about nine years
ago so nine years ago was still an
abused woman so
I am gay and I've known I've liked girls
ever since I was a little girl and I
kept it a secret for my family and my
dad I remember when the Ellen DeGeneres
came out is the first time ever heard of
the word gay before and my parents were
talking about it and I asked my dad dad
was gay and he goes it's a girl who
likes another girl and they're going to
hell and so I said okay and I walked
straight up to my room closed the door
very quietly and then I bawled my eyes
out into my pillow
and I prayed to God every day to please
let me like boys please make me straight
I knew I liked girls and so I tried I
tried pretending I liked boys and stuff
but I never did and then I met to me the
love of my life
her name is Jen and gosh it was just
like my world changed and I didn't
really care about anything else I just
knew I wanted to be near her and that
was love to me mm-hmm you know lesbian
it's not a choice mean something that is
inside you and that is that no one can
excel can help oh it's not terrible oh
it's not a disease actually because they
always say we seek we say the other
families even take us to the doctors to
the sangomas but ah it's just a day I
even had to force myself with guys to
get my friends approval and it hurts
cause had to do stuff that I don't know
I really really didn't want to do even
though I did that even as a friend of
mine who is a dude to pretend as if he's
my boyfriend but I what he did
he forced himself to me and then he left
me with HIV and that was in 2003 I did
all this just to get my Chinese approval
but now I know that I don't have to do
any one thing to please someone else in
the powers I ve done with a vitamin pill
customers expect to control it
he's from family yeah lemme see my
positive history from delayed signal
2007 a couple SEC's subdue from Ray she
becomes a genealogist you know
complicated without mama bear not really
no cure you seem more greedy I'm clearly
unhappy and you're I'm Geoffrey sector
passionately resected to rock cancer I'm
just such a fool my girl why should she
tell you an affair it's Roberta not
non-systematic empty her flippity
she paid to insulin sure but I have a
son who's near 31 years old who I love
very much his guy a gay man and a day
that he came it was quite significant I
knew that he was struggling with
something he'd been suicidal and he was
18 years old and he said to me one day
dad I've got to tell you something and I
said okay son
tell me what is it and he's he went what
he went pale Ezra he really went white
and he said I feel sick and my heart
really went out to him and at that
moment I kind of knew that he was going
to tell me he was gay
although I hadn't made that connection
because he's quite masculine and his in
his traits but just at that moment I had
a sense that that's what he was going to
tell me so I said to him son let me
let me make it easier for you I'll guess
he said yeah okay and I said you're
going to tell me you go yeah Annie
he went yes I am and and I I just I just
really really felt for him because it
was such a struggle for him to tell me
that and everything sort of made sense
because he didn't want to be guy
and that's why I'd been suicidal and so
I just got in a big hug and said I love
Vienna you I son it doesn't make any
difference how much I love you and I
think that a relationship has really
been a lot stronger since then so that's
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we have no rights over there and we have
no rights in the Arab world in general
over there and I think what I can do
more is what I've started to do is I
think I should come out even more
um I am out to my parents I am out to my
friends I am out to my work but I think
I want to encourage other people like me
which have nothing to lose because I
have a salary because my mom it's proven
with time it took a time but she's gonna
love me anyway now she knows she knows
my boyfriend she
loves me for the way I am my dad as well
my friends as well I think if you don't
tell anyone the other moms won't know
that it's okay to be gay people should
be less shy if it should be more daring
when you have nothing to lose because
some people have a lot to lose and those
are not the people that should do the
change but the ones that have nothing to
they're not shy
and in Iraq one of my friends was hit
with a car bomb in front of me and I
chased after the triggerman with my with
my squad with one of my teams and we
were just we wanted to kill that guy
cuz I can hear my buddy screaming you
know he was hurt and so we're running as
fast as we can and we're just just full
of hate and fury and we just want to do
whatever we can to just you know he hurt
our friend we're gonna get him back and
we're just running sprinting as fast as
we can with all that weight just sweat
pouring off of us through orange fields
and then we get to a clearing and yeah
it hit me I mean this blue sky it was a
old man and white robe and a child just
fill in a field you know and that just
bring me back to reality and like what
am i doing you know I'm a human being
I'm not I'm not some instrument of
revenge I guess I don't know I hate it's
just like you stop and you're like just
people doing people things here where
I'm supposed to you know all this
violence is happening and you stop and
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drought in western Maharashtra in this
country and on the one hand I was
looking at people you know facing
destitution due to a water crisis on the
other hand I was looking at
multi-storied buildings coming up with a
swimming pool on every floor we're not
talking about buildings with three
floors of four floors there is a plan
for two twin towers in Mumbai even now
under construction
37 floors each which means there are 74
swimming pools
it's a twin tower and then I went in
looked at who are the people doing the
construction who are these labourers all
the laborers were landless laborers and
marginal farmers who had left their
villages as refugees of the water crisis
and they're in the city's building are
swimming pools the sheer humiliation of
it the sheer injustice of it
I think the fastest growing sector in
India is not software or IT it is
inequality so yeah it makes me furious
it is completely unacceptable to me to
see how closely the fluence of the few
is the misery of the many I'm only like
the world like nobody bar
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you have to leave the jungle
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go show me the place we want to go to
that he said you have to go back to your
country I said where is my country I
don't have a country man it's a killing
ground it's a ground of killing the
people it's a ground of fighting it is
not a country it's a Afghanistan is not
a country now it's a killing ground man
37 countries come to control that
country but they cannot control these
people the Union cannot control these
people how can I do you have to send me
back to that country and they kid then I
lost my family in that country how can I
go to that country back I was refugee in
Pakistan I was refugee in Iran
was refuge in Dubai I was refugee and
the turkey
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and European country and Greece and I
now I'm a refugee and France but let me
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A Student Ate 5-Day-Old Pasta For Lunch.
This Is How His Liver Shutdown.
AJ is a 20 year old man, presenting to the emergency room with abdominal pain, nausea,
and diffuse bleeding.
Paramedics were scrambling because he kept vomiting in the ambulance until he fell unconscious.
AJ was a struggling college student.
Like most other people born in his time, he was looking forward to crushing student loan
debt that would wipe away his entire adult life.
The most affordable food for him was cheap pasta, cooked with premade sauce.
AJ would make all his food for the week on Sunday.
He’d refrigerate it into containers.
This way, he could ration it by day, but sometimes, he’d accidentally leave his food out overnight,
and then eat it following morning.
His friends loved to joke that one day, AJ would die of food poisoning.
Except this time, it wasn’t really a joke.
Earlier in the week, AJ accidentally left his pasta out for 2 days.
He typically would have thrown that away, but his roommate didn’t know.
He thought it may have just been out for a few hours so he put it back into the fridge.
As AJ reheated the now 5 day old pasta that was left out for 2 days, he thought it smelled
kind of strange.
But, he used a different brand of sauce this time, so he didn’t think much of it.
Immediately after finishing the entire plate of pasta, AJ’s stomach started to hurt.
He was bloating.
He could feel gas build up in his stomach and the flatulence was so embarrassing, he
had to go outside to air out his pants.
A stinging pierced through his cheeks and he could feel his eyes push out of his skull
as he suddenly vomited in a way like never before.
That pasta must have been no good, he thought.
It’s probably just a little food poisoning, he thought.
Back in his dorm room now, AJ in a world of hurt, joked to his roommate Bradley that more
than just pasta had exited his body from both ends.
Hoping that he’d feel better, he went to bed, but before that, he made sure to drink
an entire bottle of stomach medicine in hopes that it would do something for the nausea,
vomiting and diarrhea.
But it wasn’t enough.
3 am.
AJ, laying in a pool of cold sweat, runs to the bathroom to huddle over the sink for a
couple more hours.
As his roommate goes into the bathroom, he sees AJ passed out on the floor, his skin
and the whites of his eyes a sickly greenish yellow.
AJ gets up and weakly stumbles around before falling down again.
Bradley calls for 911 and AJ is brought to the emergency room where we are now.
Given this history of present illness, it’s clear that AJ is suffering from some kind
of food poisoning that is causing liver failure.
But to the medical team, that's not immediately obvious.
AJ is an otherwise healthy 20 year old man, who wasn’t taking any medicines.
Given that he’s coming from a college dorm, and he was vomiting and became unconscious,
then that sounds like it could be an alcohol poisoning case.
The yellowing of his skin and eyes is called jaundice and it comes from a chemical called
bilirubin something that makes poop brown and is produced from breaking down red blood
cells in the liver.
And if bilirubin is floating around in the blood making the skin yellow, then it means
the liver is probably damaged, which brings us back to the suspicion of alcohol poisoning
as that can damage the liver.
Similarly, another cause of liver damage and unconsciousness in a healthy, college-aged
person could be a drug overdose, of which even the roommate may not be aware.
Except, a blood test finds no evidence of alcohol or drug use.
Instead, it’s found that AJ has hypoglycemia.
Hypo meaning low.
Glyce from Ancient Greek (╬│╬╗¤ů╬║¤ů¤é) glykys meaning sweet referring to sugar.
and Emia meaning presence in blood.
Low Sugar Presence in Blood.
AJ ate his last meal of spoiled pasta about 16 hours ago.
Blood sugar levels spike after eating, and level off 4 hours after, wherein the human
body continuously works to maintain normoglycemia, but for AJ, that mechanism isn’t functioning,
meaning something that’s supposed to be releasing that sugar, isn’t releasing it.
Hypoglycemia by itself, is a relatively nonspecific problem.
It means you could have several different problems that could be causing it.
But given that the liver is the most immediate source of stored sugar, then this developing
developing hypoglycemia could give us a biochemical basis for explaining his fulminant liver failure.
You see, the liver is a highly metabolic organ.
You can’t live for very long without one.
Everything that enters your mouth, ends up in the liver, as it breaks down chemicals
and red blood cells, secretes bile for digestion, makes blood clotting factors that stop you
from bleeding, and processes proteins, among other functions, and it maintains blood sugar
levels, bringing us back to metabolism.
Sugar, or glucose is the cell’s primary source of energy, and the liver, to perform
all these functions, commands a high demand of cellular energy.
Given that glucose is no longer being released from the liver into the blood stream, then
it indicates that there is likely a metabolic problem developing inside AJ’s liver.
And because fatty acids are oxidized into glucose, which then results in ATP production,
then it means there is likely fatty deposits growing inside, stopping all essential liver
We can assume here that AJ’s food poisoning from rotten pasta is likely from some kind
of bacterial, maybe fungal source, but something’s wrong.
Typically food poisoning just causes stomach inflammation, nausea, vomiting and diarrhea.
It doesn’t typically cause acute liver failure, and even worse, we can’t find out which
bacteria is causing the problem because culturing it would take days.
Days that AJ doesn’t have, because his liver is quickly shutting down.
His response to broad spectrum antibiotics is limited.
Additional blood tests find multiple liver enzymes, floating around in his blood at a
level 500 times the upper limit of normal, meaning parts of his liver have started to
die and are circulating now all throughout his body.
His kidneys are starting to fail because analysis of his urine finds blood in it.
In liver failure, especially with the presence of bacteria, the body signals to the immune
system that something’s wrong.
White blood cells and inflammatory markers rush to the site, and vasodilate the splanchnic
From Ancient Greek splankhnikos meaning entrails.
Because about 30% of systemic blood is in the splanchnic circulation, this volume expansion
decreases the effective blood volume.
The heart detects this and secretes hormones to tell the body to hold on to water and sodium,
and to constrict all other blood vessels, including the ones going into the kidneys,
preventing blood flow in and causing acute renal injury in conjunction to fulminant hepatic
If there is no available liver for transplantation within the next day, AJ has minimal odds of
The idea of liver failure arising from toxic compounds ingested orally was not understood
until recent times.
In 1778, the ackee tree was transported to Jamaica from Western Africa by the British.
In 1875, unripened ackee fruit was consumed by people, followed by a record of vomiting,
hypoglycemia, hyperammonemia, elevated liver enzymes in blood, and fat buildup in the liver.
This was named Jamaican Vomiting Sickness.
It was found 100 years later in 1976 that hypoglycin A is the chemical that inhibits
liver mitochondrial activity, leading to fatty acid build up, hypoglycemia, hyperammonemia,
resulting in liver failure.
A famous description of aspirin overdose in children in the 1960s was published and named
Reye’s syndrome.
It was noted that children who received aspirin for fever reduction from the flu had a syndrome
of hypoglycemia, hyperammonemia, elevated liver enzymes and metabolic acidosis, symptoms
that looked very similar to those who suffered from Jamaican Vomiting Sickness.
We know today that excess aspirin uncouples the electron transport chain in mitochondria
during ATP synthesis, leading to fat buildup and liver failure.
Today, any aspirin prescribed for a child is considered a mistake and at medication
dispensing will almost always be substituted for a different drug.
For AJ, no liver was available in time for transplant and autopsy opened the opportunity
for further investigation.
Liver histologies revealed diffuse microvesicular steatosis, that is small vesicles of fat that
had accumulated inside his liver.
The cellular necrosis, that is, dead cells suggested that mitochondrial toxins were at
play meaning that bacteria may not have been the only problem with his spoiled pasta.
Post-mortem laboratory experiments and bacterial cultures were developed.
Samples of AJ’s vomit were collected while he was admitted, in addition to bile and the
pasta he ate.
The bacteria Bacillus Cereus was identified as the causative agent.
It’s well known as a foodborne pathogen that causes gastritis.
By itself, the food poisoning that results from it is usually self-limiting, meaning one can
recover from it through intrinsic bodily function.
But for AJ, a second agent was found.
Additional lab methods were used to detect, extract, isolate and purify the toxin from
Bacillus Cereus cultures, revealing the protein known as cereulide, which points us to the
final answer of AJ’s case.
Certain strains of Bacillus Cereus produce cereulide in its microenvironment.
This protein is an ionophore, meaning it has an affinity for 1 specific electronically
charged ion, namely, potassium.
For the bacteria, excess potassium is beneficial in its survival locally, but in humans this
is highly toxic.
Cereulide easily diffuses through cell membranes.
Inside, they embed onto the surface (inner membrane) of the mitochondria.
Human intracellular fluid is potassium rich, meaning it gives this toxin sufficient resources
to perform its ionophoresis, incessantly pumping potassium into the mitochondria.
This eventually overloads the ability of mitochondria to perform oxidation required to produce ATP
and energy, therefore preventing the use of glucose and fats.
The gradual swelling of the mitochondria causes it to burst, killing the cell, and on a macroscopic
scale, allows fat to pool into the liver, and causing the entire organ to fail, leading
to regional inflammation, splanchnic vasodilation, leading to the heart to release hormones for
the body to hold on to water, and to constrict the blood vessels of the kidneys, causing
kidney failure, and releasing ammonia and glutamate, that leads to swelling of the brain,
ending in death.
All because AJ unknowingly ate pasta that was left out unrefrigerated for 2 days.
The final link in this case comes not from the pasta.
but that stomach medicine AJ drank after initially vomiting
Bismuth subsalicylate is a salicylate, or more colloquially known as aspirin.
Aspirin overdoses, just like in Reye's Syndrome also result in liver failure because aspirin uncouples the electron
transport chain in mitochondria, preventing conversion of glucose into ATP, causing backing
up of glucose and pooling of fats in tissue.
So adding this medicine overdose to cereulide poisoning resulted in a dual blockade of ATP
synthesis, and leading to acute liver failure.
It’s important to note that this is NOT a typical food poisoning case.
Many people eat pasta, or any other kind of noodle that is left over for a day or two and are fine.
But tragic cases such as this one have been reported in literature, and the fulminant
hepatic failure is sudden, with patient expiration happening within hours after presenting to
the emergency room.
Some particularly tragic published cases are from families who go out on a picnic with
their children, only to have multiple small kids under 10 years old suffer from sudden
liver failure due to spoiled pasta.
And the end of those stories, are the same as in AJ's case.
Be careful of food left out for more than a few hours.
If food smells funny, it’s always better to be safe than sorry, and for cases like
cereulide poisoning, sometimes there isn’t much time left after initially eating the
spoiled food, just like for AJ.
This case was presented at a grand rounds in Illinois.
It’s based off some famous toxicology cases that all unfortunately had the same ending,
this one modified to teach residents and fellows about acute cirrhosis from microvesicular steatosis
hepatorenal syndrome, and the pathogenesis of cerebral edema in this particular
cereulide poisoning setting.
Thank you so much to all my toxicology colleagues in helping me structure this video to be palatable
for a general audience, and thank you for watching.
Take care of yourself.
And be well.